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  • Dr. Brandy Ross

Exploring the Benefits and Uses of Lithium Orotate: What You Need to Know


jar of lithium orotate salt

Lithium orotate is a nutritional supplement form of lithium, used in micro doses much like zinc or selenium. Most people, when they hear “lithium,” think of the medication used to treat bipolar disorder. Pharmaceutical lithium is available only by prescription, and is a different form of lithium called lithium carbonate. It is used in much, much higher doses, in the range of 1000 mg per day, vs. 10-20 mg per day of lithium orotate.


The prescription lithium is very potent, and is associated with several potential risks and side effects, such as tremor, acne, and fatigue. It requires regular blood tests to monitor levels in the blood and whether it is having an effect on the thyroid or kidneys.


Lithium orotate is non-prescription, and available over-the-counter like many other nutritional supplements. It is considered safe, even by the FDA, and we have not seen any problems arise when used in the recommended doses.


Lithium orotate is a mineral that has completely unique properties in terms of how it works in the brain and its impact on mood. Virtually all prescription psychiatric drugs work on the neurotransmitters, either by interacting with the receptors on the outside of the cell (the cell membrane), or by increasing the amount of a certain brain chemical like serotonin or dopamine. Lithium is able to get inside the brain cells (the neurons), affecting the inner workings of the cell itself in ways that can greatly benefit mood. Even the micro doses in lithium orotate may help calm brain activity, promote a positive mood, support emotional wellness and the brain’s natural detoxification process, provide antioxidant support, and promote the natural balance of brain neurotransmitters. 


*Note: Some supplements can cause side effects, but many people tolerate them well. They are generally considered safe, however, they should not be started without your doctor’s knowledge and supervision. If you are taking medication already, be sure to talk with your doctor before adding any of these items. If you are considering going off medication, remember never to stop your medication suddenly—always consult with your doctor about how to safely taper off any psychiatric medication.

**These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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